How To
Nasal MT2/Melanotan 2
This overview is for educational use only and assumes you're working in a research setting with proper materials and safety protocols.
Please read the important information on our main How To page before continuing.
🧪 Step-by-Step Instructions for Using Melanotan 2 (MT2)
Important: MT2 is a research peptide not approved for human use outside clinical trials. Always follow local laws and safety guidelines.
1. Gather Your Supplies
You’ll need:
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MT2 peptide (glass vial containing 10mg of peptide powder)
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Bacteriostatic or saline water, for reconstitution (this is sterile and safe to be used for injections. Once opened, any unused water must be discarded, do not keep any open water for later use)
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Alcohol swabs (these are used to wipe the skin of the injection site and the vial's rubber top before use)
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Sterile syringe with fixed needle (most people use a 1ml/100IU (international units) syringe with a fixed, 30g needle - these are very fine and cause minimal discomfort)
All required supplies are available to purchase from our store.
Ensure you are working on a clean, flat surface and that you have washed your hands with warm, soapy water and have thoroughly dried your hands with a clean, dry towel.
2. Preparing Nasal Melanotan for Use
Melanotan is sold and shipped as a dry powder in a sterile, vacuum sealed glass vial. Melanotan can not be sold pre-mixed as it would become expired if not properly refrigerated between mixing and dosing.
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Clean the area of the bacteriostatic/saline vial that you will pierce with the needle as well as the rubber seal of the Melanotan vial (remove the plastic cap) with an alcohol swab.
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Draw 1mL/100units of bacteriostatic or saline water from the vial and add to the Melanotan vial.
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Slowly inject water into the Melanotan vial, letting it run down the side to avoid damaging the peptide.
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Gently roll the vial until the mixture is dissolved.
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Add a further 1mL/100 units of bacteriostatic or saline water to the Melanotan vial.
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Gently swirl (don’t shake) until fully dissolved.
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Draw the reconstituted mixture from the Melanotan vial, adding it to the nasal spray bottle. Repeat until the Melanotan vial is empty.
3. Calculate Your Dosage
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MT2 dosing varies by research protocol. A common starting dose is 3 sprays per day for the first week, then reducing to 2 sprays per week.
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Use a dosage calculator (linked on our main "how to" page or chart to determine how much volume (in mL or IU) corresponds to your desired dose.
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Melanotan is active in the body for 36h after injection, for the best possible results you should get some UV rays within this time.
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Timing - most people when just starting to use melanotan will experience mild nausea and facial flushing right after the injection, for this reason it is advisable to take the injections just before going to bed so you sleep it off.
4. Administer the Dose
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Clean the nasal tube of the nasal spray bottle.
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Insert this into one nostril.
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While snorting back, administer 3 sprays to that nostril.
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Repeat this daily, for the first week, swapping between nostrils each day.
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After the first week, follow the above steps but only for one day per week, reducing to 2 sprays on the day you administer.
Once established, Melanotan use should not exceed 2 days per week for 8 weeks on, followed by an 8 week break.
Storage and Safety
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Store reconstituted MT2 in the fridge (2–8°C).
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Use within 30 days of mixing.
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Keep all materials sterile and dispose of sharps properly.
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Do not pre-make syringes.
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Do not re-use syringes.

